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Octopus is a research project aimed at finding treatments that can slow down disability progression in people with MS.

Read more here www.ms-octopus.info

As of January 2024, there are 12 hospital sites now open to enrolment in Octopus. These sites are reaching out to people who have already registered an interest and may be eligible after completing the form. The hospital site teams will arrange a call or contact you by email to discuss your answers in more detail, to see if you are suitable to take part.

Please be aware of these important things to know:
  • We are delighted there has been a large amount of interest in becoming a participant in Octopus More than 2500 people with MS have registered their interest in the trial.
  • Octopus will run until at least 2028 and will have 2 stages. Stage 1 needs 375 participants (aim is to complete in December 2024). Stage 2 will start in 2025 and will recruit about 825 more participants until around 2028.
  • Some sites have more potential participants registered than needed for the first stage, so they may not contact new registrants until 2025 or later. These hospital sites are:
    • Leeds General Infirmary
    • The Anne Rowling Regenerative Neurology Clinic Edinburgh
    • University College Hospital London
    • University Hospital Southampton

Other sites may still need participants. We encourage you to register and join the waiting list to be kept updated on the trial. Please still bear in mind you may not be contacted by your chosen site until at least 2025. Priority will be given to participants based on their registration date and also to those close to 70 years old.

If you are happy to be put onto the waiting list, you can show your interest in taking part in Octopus by filling in the Registration of interest form. You will be able to check if you might be potentially eligible for Octopus and let us know which Octopus hospital site you prefer.

Octopus will be open and recruiting participants until at least 2028 or beyond. We will keep you posted on the trial progress including when the next stage begins. If you would like more information or updates on Octopus, please visit:

If you are already on the MS Register you can sign up to Octopus here:

Login to MS Register

By registering your interest, you are agreeing to the MS Register sharing the data you provide with researchers at UCL to assess your eligibility for the Octopus trial.

Register my interest